Cardiovascular diseases-related GNB3 C825T polymorphism has a significant sex-specific effect on serum soluble E-selectin levels
نویسندگان
چکیده
منابع مشابه
Soluble E-selectin and P-Selectin Serum Levels in Patients with Psoriasis Compared to Healthy Controls
Introduction: Psoriasis is an inflammatory skin disease in which abnormal individual immune reactivity plays an important role. Eselectin and P-selectin are adhesion molecules expressed on vascular endothelial cells in several inflammatory skin diseases, including psoriasis. The aim of the present study was to describe selected immunological changes, concerning adhesion molecules status (sEsele...
متن کاملVasovagal syncope patients and the C825T GNB3 polymorphism.
OBJECTIVE The G protein is responsible for signal intracellular transduction and participates in cardiovascular reflexes. C825T polymorphism of the gene encodes the B3 subunit of G protein (GNB3) and causes the increased intracellular signal transduction. The aim was the evaluation GNB3 C825T polymorphism manifestation in vasovagal patients with no other diseases. METHODS In 68 positive tilte...
متن کاملLevels of Serum Soluble P-Selectin and E-Selectin in Psoriatıc Patients
Vol. 26 No. 2, 2014 275 Received January 3, 2013, Revised April 6, 2013, Accepted for publication May 14, 2013 *Recep Kesli is now with Department of Microbiology, Afyon University Faculty of Medicine, Afyonkarahisar, Turkey. Corresponding author: Arzu Ataseven, Department of Dermatology, Konya Training and Research Hospital, Meram, Konya 42090, Turkey. Tel: 90-0 505 691 58 59, Fax: 90-0 332 32...
متن کاملThe C825T GNB3 polymorphism, independent of blood pressure, predicts cerebrovascular risk at a population level.
BACKGROUND The role of C825T polymorphism of the candidate GNB3 gene in predicting cerebrovascular outcome has been poorly explored in longitudinal setting at a population level. METHODS In an epidemiological setting, 1,678 men and women from general population were genotyped for C825T polymorphism of GNB3 gene and follow-up for 10 years to detect nonfatal and fatal cerebrovascular events (CE...
متن کاملCirculating soluble E-selectin levels and the Ser 128Arg polymorphism in individuals from different ethnic groups.
BACKGROUND AND AIM An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population. The aim of this study was to investigate whether the Ser128 Arg polymorphism of the E-selectin gene is associated with soluble E-selectin levels in individuals from a multiethnic population. METHODS AND RESULTS Plasma sE-selectin levels...
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ژورنال
عنوان ژورنال: Journal of Inflammation
سال: 2016
ISSN: 1476-9255
DOI: 10.1186/s12950-016-0146-z